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Diallyl disulfide inhibits colon cancer metastasis by suppressing Rac1-mediated epithelial-mesenchymal transition

BACKGROUND: Prevention of epithelial-mesenchymal transition (EMT) provides a novel treatment strategy for tumor metastasis. Our previous studies have shown that diallyl disulfide (DADS) inhibits Ras related C3 botulinum toxin substrate1 (Rac1) expression, being a potential agent that suppresses migr...

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Detalles Bibliográficos
Autores principales: Xia, Longzheng, Lin, Jingguan, Su, Jian, Oyang, Linda, Wang, Heran, Tan, Shiming, Tang, Yanyan, Chen, Xiaoyan, Liu, Wenbin, Luo, Xia, Tian, Yutong, Liang, Jiaxin, Su, Qi, Liao, Qianjin, Zhou, Yujuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6645609/
https://www.ncbi.nlm.nih.gov/pubmed/31410018
http://dx.doi.org/10.2147/OTT.S208738