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Self-nanoemulsifying ramipril tablets: a novel delivery system for the enhancement of drug dissolution and stability
Background: Ramipril (RMP) suffers from poor aqueous solubility along with sensitivity to mechanical stress, heat, and moisture. The aim of the current study is to improve RMP solubility and stability by designing solid self-nanoemulsifying drug delivery system (S-SNEDDS) as tablet. Methods: The dru...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6645612/ https://www.ncbi.nlm.nih.gov/pubmed/31409997 http://dx.doi.org/10.2147/IJN.S203311 |