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Self-nanoemulsifying ramipril tablets: a novel delivery system for the enhancement of drug dissolution and stability

Background: Ramipril (RMP) suffers from poor aqueous solubility along with sensitivity to mechanical stress, heat, and moisture. The aim of the current study is to improve RMP solubility and stability by designing solid self-nanoemulsifying drug delivery system (S-SNEDDS) as tablet. Methods: The dru...

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Detalles Bibliográficos
Autores principales: Alhasani, Khalid F, Kazi, Mohsin, Ibrahim, Mohamed Abbas, Shahba, Ahmad A, Alanazi, Fars K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6645612/
https://www.ncbi.nlm.nih.gov/pubmed/31409997
http://dx.doi.org/10.2147/IJN.S203311