Preparation and evaluation of tacrolimus-loaded thermosensitive solid lipid nanoparticles for improved dermal distribution

Background: Tacrolimus (TCR), also known as FK-506, is a biopharmaceutics classification system (BCS) class II drug that is insoluble in water because of its high log P values. After dermal application, TCR remains in the stratum corneum and passes through the skin layers with difficulty. Purpose: T...

Descripción completa

Detalles Bibliográficos
Autores principales: Kang, Ji-Hyun, Chon, Jinmann, Kim, Young-Il, Lee, Hyo-Jung, Oh, Dong-Won, Lee, Hong-Goo, Han, Chang-Soo, Kim, Dong-Wook, Park, Chun-Woong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6645695/
https://www.ncbi.nlm.nih.gov/pubmed/31409994
http://dx.doi.org/10.2147/IJN.S215153

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6645695/
https://www.ncbi.nlm.nih.gov/pubmed/31409994
http://dx.doi.org/10.2147/IJN.S215153

Ejemplares similares