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Preparation and evaluation of tacrolimus-loaded thermosensitive solid lipid nanoparticles for improved dermal distribution

Background: Tacrolimus (TCR), also known as FK-506, is a biopharmaceutics classification system (BCS) class II drug that is insoluble in water because of its high log P values. After dermal application, TCR remains in the stratum corneum and passes through the skin layers with difficulty. Purpose: T...

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Detalles Bibliográficos
Autores principales:	Kang, Ji-Hyun, Chon, Jinmann, Kim, Young-Il, Lee, Hyo-Jung, Oh, Dong-Won, Lee, Hong-Goo, Han, Chang-Soo, Kim, Dong-Wook, Park, Chun-Woong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6645695/ https://www.ncbi.nlm.nih.gov/pubmed/31409994 http://dx.doi.org/10.2147/IJN.S215153

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