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Oridonin overcomes the gemcitabine resistant PANC-1/Gem cells by regulating GST pi and LRP/1 ERK/JNK signalling

Background: Chemotherapy remains a primary treatment method for advanced pancreatic cancer. However, chemotherapy resistance can influence the therapeutic effect of pancreatic cancer. The resistance mechanism of chemotherapeutic agents such as gemcitabine, which is an agent typically used to treat p...

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Detalles Bibliográficos
Autores principales: Wang, Bili, Shen, Can, Li, Yang, Zhang, Ting, Huang, Hui, Ren, Jun, Hu, Zhengjun, Xu, Jian, Xu, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6645696/
https://www.ncbi.nlm.nih.gov/pubmed/31410021
http://dx.doi.org/10.2147/OTT.S208924