Ethanol induces interferon expression in neurons via TRAIL: role of astrocyte-to-neuron signaling

RATIONALE: Alcohol use disorder (AUD) involves dysregulation of innate immune signaling in brain. Toll-like receptor 3 (TLR3), an innate immune receptor that is upregulated in post-mortem human alcoholics, leads to induction of interferon (IFN) signaling. IFNs have been linked to depressive-like sym...

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Detalles Bibliográficos
Autores principales: Lawrimore, Colleen J., Coleman, Leon G., Crews, Fulton T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646093/
https://www.ncbi.nlm.nih.gov/pubmed/30610351
http://dx.doi.org/10.1007/s00213-018-5153-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646093/
https://www.ncbi.nlm.nih.gov/pubmed/30610351
http://dx.doi.org/10.1007/s00213-018-5153-8

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