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Ethanol induces interferon expression in neurons via TRAIL: role of astrocyte-to-neuron signaling
RATIONALE: Alcohol use disorder (AUD) involves dysregulation of innate immune signaling in brain. Toll-like receptor 3 (TLR3), an innate immune receptor that is upregulated in post-mortem human alcoholics, leads to induction of interferon (IFN) signaling. IFNs have been linked to depressive-like sym...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646093/ https://www.ncbi.nlm.nih.gov/pubmed/30610351 http://dx.doi.org/10.1007/s00213-018-5153-8 |