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Systems biology and network pharmacology of frailty reveal novel epigenetic targets and mechanisms

Frailty is an age-associated condition, characterized by an inappropriate response to stress that results in a higher frequency of adverse outcomes (e.g., mortality, institutionalization and disability). Some light has been shed over its genetic background, but this is still a matter of debate. In t...

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Detalles Bibliográficos
Autores principales: Gomez-Verjan, J. C., Ramírez-Aldana, R., Pérez-Zepeda, M. U., Quiroz-Baez, R., Luna-López, A., Gutierrez Robledo, L. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646318/
https://www.ncbi.nlm.nih.gov/pubmed/31332237
http://dx.doi.org/10.1038/s41598-019-47087-7