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ADAMTS Sol narae cleaves extracellular Wingless to generate a novel active form that regulates cell proliferation in Drosophila

Wnt/ Wingless (Wg) is essential for embryonic development and adult homeostasis in all metazoans, but the mechanisms by which secreted Wnt/Wg is processed remain largely unknown. A Drosophila Sol narae (Sona) is a member of A Disintegrin And Metalloprotease with ThromboSpondin motif (ADAMTS) family,...

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Detalles Bibliográficos
Autores principales: Won, Jong-Hoon, Kim, Go-Woon, Kim, Ja-Young, Cho, Dong-Gyu, Kwon, Buki, Bae, Young-Kyung, Cho, Kyung-Ok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646336/
https://www.ncbi.nlm.nih.gov/pubmed/31332194
http://dx.doi.org/10.1038/s41419-019-1794-8