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Homocysteine enhances neural stem cell autophagy in in vivo and in vitro model of ischemic stroke

The elevated level of the amino acid metabolite homocysteine (Hcy) is known as a risk factor for ischemic stroke. The molecular mechanisms responsible for neurotoxicity of Hcy remain largely unknown in ischemic brains. The previous studies have shown that Hcy decreases the proliferation and viabilit...

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Detalles Bibliográficos
Autores principales: Wang, Mengying, Liang, Xiaoshan, Cheng, Man, Yang, Liu, Liu, Huan, Wang, Xuan, Sai, Na, Zhang, Xumei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646339/
https://www.ncbi.nlm.nih.gov/pubmed/31332165
http://dx.doi.org/10.1038/s41419-019-1798-4