Integrated analyses of murine breast cancer models reveal critical parallels with human disease

Mouse models have an essential role in cancer research, yet little is known about how various models resemble human cancer at a genomic level. Here, we complete whole genome sequencing and transcriptome profiling of two widely used mouse models of breast cancer, MMTV-Neu and MMTV-PyMT. Through integ...

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Detalles Bibliográficos
Autores principales: Rennhack, Jonathan P., To, Briana, Swiatnicki, Matthew, Dulak, Caleb, Ogrodzinski, Martin P., Zhang, Yueqi, Li, Caralynn, Bylett, Evan, Ross, Christina, Szczepanek, Karol, Hanrahan, William, Jayatissa, Muthu, Lunt, Sophia Y., Hunter, Kent, Andrechek, Eran R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646342/
https://www.ncbi.nlm.nih.gov/pubmed/31332182
http://dx.doi.org/10.1038/s41467-019-11236-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646342/
https://www.ncbi.nlm.nih.gov/pubmed/31332182
http://dx.doi.org/10.1038/s41467-019-11236-3

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