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Mitofusin 1 is required for female fertility and to maintain ovarian follicular reserve

Mitochondria are dynamic organelles that continually adapt their structure through fusion and fission in response to changes in their bioenergetic environment. Targeted deletion of mitochondrial fusion protein mitofusin1 (MFN1) in oocytes resulted in female infertility associated with failure to ach...

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Detalles Bibliográficos
Autores principales: Zhang, Man, Bener, Muhammed Burak, Jiang, Zongliang, Wang, Tianren, Esencan, Ecem, Scott III, Richard, Horvath, Tamas, Seli, Emre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646343/
https://www.ncbi.nlm.nih.gov/pubmed/31332167
http://dx.doi.org/10.1038/s41419-019-1799-3