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Mitofusin 1 is required for female fertility and to maintain ovarian follicular reserve
Mitochondria are dynamic organelles that continually adapt their structure through fusion and fission in response to changes in their bioenergetic environment. Targeted deletion of mitochondrial fusion protein mitofusin1 (MFN1) in oocytes resulted in female infertility associated with failure to ach...
Autores principales: | Zhang, Man, Bener, Muhammed Burak, Jiang, Zongliang, Wang, Tianren, Esencan, Ecem, Scott III, Richard, Horvath, Tamas, Seli, Emre |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646343/ https://www.ncbi.nlm.nih.gov/pubmed/31332167 http://dx.doi.org/10.1038/s41419-019-1799-3 |
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