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ERβ promotes Aβ degradation via the modulation of autophagy

Alzheimer’s Disease (AD) is the most common neurodegenerative disorder in the elderly. Beta-amyloid (Aβ) peptide accumulation is considered as a primary cause of AD pathogenesis, with defective autophagy in patients’ brains. Enhanced autophagic activity has been reported to promote Aβ clearance in v...

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Detalles Bibliográficos
Autores principales: Wei, Yong, Zhou, Jiawei, Wu, Jun, Huang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646346/
https://www.ncbi.nlm.nih.gov/pubmed/31332160
http://dx.doi.org/10.1038/s41419-019-1786-8