Parvalbumin expression in oligodendrocyte-like CG4 cells causes a reduction in mitochondrial volume, attenuation in reactive oxygen species production and a decrease in cell processes’ length and branching

Forebrain glial cells - ependymal cells and astrocytes -acquire upon injury- a “reactive” phenotype associated with parvalbumin (PV) upregulation. Since free radicals, e.g. reactive oxygen species (ROS) play a role in the pathogenesis of multiple sclerosis, and that PV-upregulation in glial cells is...

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Detalles Bibliográficos
Autores principales: Lichvarova, Lucia, Blum, Walter, Schwaller, Beat, Szabolcsi, Viktoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646370/
https://www.ncbi.nlm.nih.gov/pubmed/31332265
http://dx.doi.org/10.1038/s41598-019-47112-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646370/
https://www.ncbi.nlm.nih.gov/pubmed/31332265
http://dx.doi.org/10.1038/s41598-019-47112-9

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