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Predicting Synergism of Cancer Drug Combinations Using NCI-ALMANAC Data

Drug combinations are of great interest for cancer treatment. Unfortunately, the discovery of synergistic combinations by purely experimental means is only feasible on small sets of drugs. In silico modeling methods can substantially widen this search by providing tools able to predict which of all...

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Detalles Bibliográficos
Autores principales: Sidorov, Pavel, Naulaerts, Stefan, Ariey-Bonnet, Jérémy, Pasquier, Eddy, Ballester, Pedro J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646421/
https://www.ncbi.nlm.nih.gov/pubmed/31380352
http://dx.doi.org/10.3389/fchem.2019.00509