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Regulation of DNA Double Strand Breaks Processing: Focus on Barriers

In all the eukaryotic cells, nucleolytic processing (resection) of a double strand DNA break (DSB) is a key step to channel the repair of the lesion toward the homologous recombination, at the expenses of the non-homologous end joining (NHEJ). The coordinated action of several nucleases and helicase...

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Detalles Bibliográficos
Autores principales: Marini, Federica, Rawal, Chetan C., Liberi, Giordano, Pellicioli, Achille
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646425/
https://www.ncbi.nlm.nih.gov/pubmed/31380392
http://dx.doi.org/10.3389/fmolb.2019.00055