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Drug Holiday of Interferon Beta 1b in Multiple Sclerosis: A Pilot, Randomized, Single Blind Study of Non-inferiority

Introduction: To compare a schedule with cyclic withdrawal (CW) of interferon beta (IFN-b) 1b, respect to the full regimen (FR), in relapsing-remitting MS (RR-MS). Methods: Participants were randomly assigned to CW or FR schedule and monthly monitored with brain MRI scans for 12 months (three of run...

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Detalles Bibliográficos
Autores principales: Romano, Silvia, Ferraldeschi, Michela, Bagnato, Francesca, Mechelli, Rosella, Morena, Emanuele, Caldano, Marzia, Buscarinu, Maria Chiara, Fornasiero, Arianna, Frontoni, Marco, Nociti, Viviana, Mirabella, Massimiliano, Mayer, Flavia, Bertolotto, Antonio, Pozzilli, Carlo, Vanacore, Nicola, Salvetti, Marco, Ristori, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646514/
https://www.ncbi.nlm.nih.gov/pubmed/31379701
http://dx.doi.org/10.3389/fneur.2019.00695