Flow Cytometric Determination of Actin Polymerization in Peripheral Blood Leukocytes Effectively Discriminate Patients With Homozygous Mutation in ARPC1B From Asymptomatic Carriers and Normal Controls

Actin nucleators initiate formation of actin filaments. Among them, the Arp2/3 complex has the ability to form branched actin networks. This complex is regulated by members of the Wiscott-Aldrich syndrome protein (WASp) family. Polymerization of actin filaments can be evaluated through flow cytometr...

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Detalles Bibliográficos
Autores principales: Kopitar, Andreja N., Markelj, Gašper, Oražem, Miha, Blazina, Štefan, Avčin, Tadej, Ihan, Alojz, Debeljak, Maruša
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646687/
https://www.ncbi.nlm.nih.gov/pubmed/31379835
http://dx.doi.org/10.3389/fimmu.2019.01632

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646687/
https://www.ncbi.nlm.nih.gov/pubmed/31379835
http://dx.doi.org/10.3389/fimmu.2019.01632

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