Cargando…

Flow Cytometric Determination of Actin Polymerization in Peripheral Blood Leukocytes Effectively Discriminate Patients With Homozygous Mutation in ARPC1B From Asymptomatic Carriers and Normal Controls

Actin nucleators initiate formation of actin filaments. Among them, the Arp2/3 complex has the ability to form branched actin networks. This complex is regulated by members of the Wiscott-Aldrich syndrome protein (WASp) family. Polymerization of actin filaments can be evaluated through flow cytometr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kopitar, Andreja N., Markelj, Gašper, Oražem, Miha, Blazina, Štefan, Avčin, Tadej, Ihan, Alojz, Debeljak, Maruša
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646687/ https://www.ncbi.nlm.nih.gov/pubmed/31379835 http://dx.doi.org/10.3389/fimmu.2019.01632

Ejemplares similares

Functional Complement Analysis Can Predict Genetic Testing Results and Long-Term Outcome in Patients With Complement Deficiencies
por: Blazina, Štefan, et al.
Publicado: (2018)

Case report: Pneumocystis jirovecii pneumonia in a severe case of Aicardi–Goutières syndrome with an IFIH1 gain-of-function mutation mimicking combined immunodeficiency
por: Železnik, Mojca, et al.
Publicado: (2023)

Inflammatory Molecules in Aqueous Humour and on Ocular Surface and Glaucoma Surgery Outcome
por: Cvenkel, Barbara, et al.
Publicado: (2010)

Alterations in immunophenotype and metabolic profile of mononuclear cells during follow up in children with multisystem inflammatory syndrome (MIS-C)
por: Kopitar, Andreja Nataša, et al.
Publicado: (2023)

Inhibition of cathepsin X enzyme influences the immune response of THP-1 cells and dendritic cells infected with Helicobacter pylori
por: Skvarc, Miha, et al.
Publicado: (2013)

Age-Related Differences in Percentages of Regulatory and Effector T Lymphocytes and Their Subsets in Healthy Individuals and Characteristic STAT1/STAT5 Signalling Response in Helper T Lymphocytes
por: Holcar, Marija, et al.
Publicado: (2015)

MEFV and NLRP3 gene variants in children with pfapa syndrome in slovenia
por: Perko, Daša, et al.
Publicado: (2014)

Clinical Features and Genetic Background of the Periodic Fever Syndrome with Aphthous Stomatitis, Pharyngitis, and Adenitis: A Single Center Longitudinal Study of 81 Patients
por: Perko, Daša, et al.
Publicado: (2015)

Therapeutic electric stimulation does not affect immune status in healthy individuals – a preliminary report
por: Kopitar, Andreja N, et al.
Publicado: (2012)

Prescribing adrenaline auto-injectors in Slovenian children
por: Vesel, Tina, et al.
Publicado: (2015)

Macrophage polarization during Streptococcus agalactiae infection is isolate specific
por: Janžič, Larisa, et al.
Publicado: (2023)

The spectrum of clinical presentation in haploinsufficiency of A20; a case report of a novel mutation in TNFAIP3 gene
por: Debeljak, M., et al.
Publicado: (2023)

Comparison of Lymphocyte Populations in Patients With Dobrava or Puumala orthohantavirus Infection
por: Resman Rus, Katarina, et al.
Publicado: (2020)

Effect of surgery and radiotherapy on complete blood count, lymphocyte subsets and inflammatory response in patients with advanced oral cancer
por: Dovšak, Tadej, et al.
Publicado: (2018)

The role of IL-1 inhibition in systemic juvenile idiopathic arthritis: current status and future perspectives
por: Toplak, Nataša, et al.
Publicado: (2018)

Dendritic Cell Profiles in the Inflamed Colonic Mucosa Predict the Responses to Tumor Necrosis Factor Alpha Inhibitors in Inflammatory Bowel Disease
por: Smrekar, Natasa, et al.
Publicado: (2018)

Effect of Cryopreserved Amniotic Membrane Orientation on the Expression of Limbal Mesenchymal and Epithelial Stem Cell Markers in Prolonged Limbal Explant Cultures
por: Lužnik, Zala, et al.
Publicado: (2016)

Dendritic cell activation and cytokine response in vaccine breakthrough TBE patients after in vitro stimulation with TBEV
por: Marušić, Miša, et al.
Publicado: (2023)

Extracellular Vesicles Derived Human-miRNAs Modulate the Immune System in Type 1 Diabetes
por: Tesovnik, Tine, et al.
Publicado: (2020)

Genetic determinants of methotrexate treatment efficacy in patients with juvenile idiopathic arthritis
por: Avramovič, Mojca Zajc, et al.
Publicado: (2014)

PIK3AP1 and SPON2 Genes Are Differentially Methylated in Patients With Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Adenitis (PFAPA) Syndrome
por: Lovšin, Ema, et al.
Publicado: (2020)

Actin polymerization inhibition by targeting ARPC2 affects intestinal stem cell homeostasis
por: Zhang, Ruzhen, et al.
Publicado: (2023)

Integrative Transcriptomic Profiling of the Wilms Tumor
por: Avčin, Simona Lucija, et al.
Publicado: (2023)

ARPC1B binds WASP to control actin polymerization and curtail tonic signaling in B cells
por: Leung, Gabriella, et al.
Publicado: (2021)

Role of ARPC2 in Human Gastric Cancer
por: Zhang, Jun, et al.
Publicado: (2017)

Clinical and genetic characteristics of a patient with phosphoribosyl pyrophosphate synthetase 1 deficiency and a systematic literature review
por: Štajer, Katarina, et al.
Publicado: (2023)

Targeting of the Arpc3 actin nucleation factor by miR-29a/b regulates dendritic spine morphology
por: Lippi, Giordano, et al.
Publicado: (2011)

ARPC2 promotes breast cancer proliferation and metastasis
por: Cheng, Zhongle, et al.
Publicado: (2019)

Cryo-EM of human Arp2/3 complexes provides structural insights into actin nucleation modulation by ARPC5 isoforms
por: von Loeffelholz, Ottilie, et al.
Publicado: (2020)

A recurrent, de novo pathogenic variant in ARPC4 disrupts actin filament formation and causes microcephaly and speech delay
por: Laboy Cintron, Dianne, et al.
Publicado: (2021)

PReS-FINAL-2314: Anti-TNF alpha therapy for refractory childhood takayasu arthritis
por: Koren, B, et al.
Publicado: (2013)

Distribution of MEFV gene mutations and R202Q polymorphism in the Serbian population and their influence on oxidative stress and clinical manifestations of inflammation
por: Milenković, Jelena, et al.
Publicado: (2016)

The Expression of Actin-Related Protein 2/3 Complex Subunit 5 (ARPC5) Expression in Multiple Myeloma and its Prognostic Significance
por: Xiong, Tao, et al.
Publicado: (2018)

ARPC1B Mutation Manifesting as Recurrent Hematemesis With Metaplasia
por: Antala, Swati, et al.
Publicado: (2021)

Clinical Impacts of Copy Number Variations in B-cell Differentiation and Cell Cycle Control Genes in Pediatric B-cell Acute Lymphoblastic Leukemia: a Single Centre Experience
por: Crepinsek, Klementina, et al.
Publicado: (2021)

Flow Cytometric Analysis of Leukocyte Populations in the Lung Tissue of Dromedary Camels
por: Hussen, Jamal, et al.
Publicado: (2022)

CRISPR-Cas9 Arabidopsis mutants of genes for ARPC1 and ARPC3 subunits of ARP2/3 complex reveal differential roles of complex subunits
por: Bellinvia, Erica, et al.
Publicado: (2022)

Survival of castration‐resistant prostate cancer patients treated with dendritic–tumor cell hybridomas is negatively correlated with changes in peripheral blood CD56(bright)CD16(−) natural killer cells
por: Haque Chowdhury, Helena, et al.
Publicado: (2021)

Effectiveness of a Simply Designed Tumor Vaccine in Prevention of Malignant Melanoma Development
por: Novakovic, Srdjan, et al.
Publicado: (1999)

An In Vitro Evaluation of the Red Cell Damage and Hemocompatibility of Different Central Venous Catheters
por: Ihan, Alojz, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_ndsko2ol8pshecn6qfglp1j4f5