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Bone Marrow Mesenchymal Stromal Cell Treatment in Patients with Osteoarthritis Results in Overall Improvement in Pain and Symptoms and Reduces Synovial Inflammation

Patients with late‐stage Kellgren‐Lawrence knee osteoarthritis received a single intra‐articular injection of 1, 10, or 50 million bone marrow mesenchymal stromal cells (BM‐MSCs) in a phase I/IIa trial to assess safety and efficacy using a broad toolset of analytical methods. Besides safety, outcome...

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Detalles Bibliográficos
Autores principales: Chahal, Jaskarndip, Gómez‐Aristizábal, Alejandro, Shestopaloff, Konstantin, Bhatt, Shashank, Chaboureau, Amélie, Fazio, Antonietta, Chisholm, Jolene, Weston, Amanda, Chiovitti, Julia, Keating, Armand, Kapoor, Mohit, Ogilvie‐Harris, Darrell J., Syed, Khalid A., Gandhi, Rajiv, Mahomed, Nizar N., Marshall, Kenneth W., Sussman, Marshall S., Naraghi, Ali M., Viswanathan, Sowmya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646697/
https://www.ncbi.nlm.nih.gov/pubmed/30964245
http://dx.doi.org/10.1002/sctm.18-0183