Novel CaM-binding motif in its NudT9H domain contributes to temperature sensitivity of TRPM2

TRPM2 is a non-selective, Ca(2+)-permeable cation channel, which plays a role in cell death but also contributes to diverse immune cell functions. In addition, TRPM2 contributes to the control of body temperature and is involved in perception of non-noxious heat and thermotaxis. TRPM2 is regulated b...

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Detalles Bibliográficos
Autores principales: Gattkowski, Ellen, Johnsen, Anke, Bauche, Andreas, Möckl, Franziska, Kulow, Frederike, Garcia Alai, Maria, Rutherford, Trevor J., Fliegert, Ralf, Tidow, Henning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646794/
https://www.ncbi.nlm.nih.gov/pubmed/30584900
http://dx.doi.org/10.1016/j.bbamcr.2018.12.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646794/
https://www.ncbi.nlm.nih.gov/pubmed/30584900
http://dx.doi.org/10.1016/j.bbamcr.2018.12.010

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