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Novel CaM-binding motif in its NudT9H domain contributes to temperature sensitivity of TRPM2
TRPM2 is a non-selective, Ca(2+)-permeable cation channel, which plays a role in cell death but also contributes to diverse immune cell functions. In addition, TRPM2 contributes to the control of body temperature and is involved in perception of non-noxious heat and thermotaxis. TRPM2 is regulated b...
Autores principales: | Gattkowski, Ellen, Johnsen, Anke, Bauche, Andreas, Möckl, Franziska, Kulow, Frederike, Garcia Alai, Maria, Rutherford, Trevor J., Fliegert, Ralf, Tidow, Henning |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646794/ https://www.ncbi.nlm.nih.gov/pubmed/30584900 http://dx.doi.org/10.1016/j.bbamcr.2018.12.010 |
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