Gain‐of‐function experiments with bacteriophage lambda uncover residues under diversifying selection in nature

Viral gain‐of‐function mutations frequently evolve during laboratory experiments. Whether the specific mutations that evolve in the lab also evolve in nature and whether they have the same impact on evolution in the real world is unknown. We studied a model virus, bacteriophage λ, that repeatedly ev...

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Detalles Bibliográficos
Autores principales: Maddamsetti, Rohan, Johnson, Daniel T., Spielman, Stephanie J., Petrie, Katherine L., Marks, Debora S., Meyer, Justin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Brief Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646904/
https://www.ncbi.nlm.nih.gov/pubmed/30152871
http://dx.doi.org/10.1111/evo.13586

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646904/
https://www.ncbi.nlm.nih.gov/pubmed/30152871
http://dx.doi.org/10.1111/evo.13586

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