Epac1(−/−) mice have elevated baseline permeability and do not respond to histamine as measured with dynamic contrast‐enhanced magnetic resonance imaging with contrast agents of different molecular weights

AIM: Epac1(−/−) mice, but not Epac2(−/−) mice have elevated baseline permeability to albumin. This study extends the investigations of how Epac‐dependent pathways modulate transvascular exchange in response to the classical inflammatory agent histamine. It also evaluates the limitations of models of...

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Detalles Bibliográficos
Autores principales: Curry, Fitz‐Roy E., Taxt, Torfinn, Rygh, Cecilie Brekke, Pavlin, Tina, Bjønrstad, Ronja, Døskeland, Stein Ove, Reed, Rolf K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Renal Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646910/
https://www.ncbi.nlm.nih.gov/pubmed/30300965
http://dx.doi.org/10.1111/apha.13199

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646910/
https://www.ncbi.nlm.nih.gov/pubmed/30300965
http://dx.doi.org/10.1111/apha.13199

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