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Epac1(−/−) mice have elevated baseline permeability and do not respond to histamine as measured with dynamic contrast‐enhanced magnetic resonance imaging with contrast agents of different molecular weights
AIM: Epac1(−/−) mice, but not Epac2(−/−) mice have elevated baseline permeability to albumin. This study extends the investigations of how Epac‐dependent pathways modulate transvascular exchange in response to the classical inflammatory agent histamine. It also evaluates the limitations of models of...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646910/ https://www.ncbi.nlm.nih.gov/pubmed/30300965 http://dx.doi.org/10.1111/apha.13199 |