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MiR-34c acts as a tumor suppressor in non-small cell lung cancer by inducing endoplasmic reticulum stress through targeting HMGB1

OBJECTIVE: To investigate the role of miR-34c in lung cancer. METHODS: The levels of microRNA-34c (miR-34c) expression in non-small cell lung cancer (NSCLC) tissue and cell lines were examined by the qRT-PCR assay. High mobility group box 1 (HMGB1) expression in NSCLC was assessed by immunohistochem...

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Detalles Bibliográficos
Autores principales: Tu, Li, Long, Xiang, Song, Weidong, Lv, Zhongdong, Zeng, Huadong, Wang, Tiezhu, Liu, Xianglu, Dong, Juanni, Xu, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647009/
https://www.ncbi.nlm.nih.gov/pubmed/31410019
http://dx.doi.org/10.2147/OTT.S206932