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Effect of MMP-2 gene silencing on radiation-induced DNA damage in human normal dermal fibroblasts and breast cancer cells

INTRODUCTION: Diagnostic and therapeutic ionizing radiation (IR) is one of the well known long term risk factors of breast cancer. Extremely lethal consequences of IR causes double-strand breaks, which are mainly responsible for genomic instability, altered gene expression, and cell death. FINDINGS:...

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Detalles Bibliográficos
Autores principales: Shailender, Gugalavath, Kumari, Seema, Kiranmayi, Patnala, Malla, Rama Rao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647068/
https://www.ncbi.nlm.nih.gov/pubmed/31367263
http://dx.doi.org/10.1186/s41021-019-0131-x