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TNF blockade contributes to restore lipid oxidation during exercise in children with juvenile idiopathic arthritis

BACKGROUND: Children with juvenile idiopathic arthritis (JIA) have impaired physical abilities. TNF-α plays a crucial role in this pathogenesis, but it is also involved in the use of lipids and muscle health. Objective of this study was to explore substrate oxidation and impact of TNF blockade on en...

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Detalles Bibliográficos
Autores principales: Rochette, Emmanuelle, Bourdier, Pierre, Pereira, Bruno, Doré, Eric, Birat, Anthony, Ratel, Sébastien, Echaubard, Stéphane, Duché, Pascale, Merlin, Etienne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647146/
https://www.ncbi.nlm.nih.gov/pubmed/31331342
http://dx.doi.org/10.1186/s12969-019-0354-1