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Genome editing of human pancreatic beta cell models: problems, possibilities and outlook
Understanding the molecular mechanisms behind beta cell dysfunction is essential for the development of effective and specific approaches for diabetes care and prevention. Physiological human beta cell models are needed for this work. We review the possibilities and limitations of currently availabl...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647170/ https://www.ncbi.nlm.nih.gov/pubmed/31161346 http://dx.doi.org/10.1007/s00125-019-4908-z |