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Sphingosine-coating of plastic surfaces prevents ventilator-associated pneumonia

ABSTRACT: Ventilator-associated pneumonia (VAP) is a major cause of morbidity and mortality in critically ill patients. Here, we employed the broad antibacterial effects of sphingosine to prevent VAP by developing a novel method of coating surfaces of endotracheal tubes with sphingosine and sphingos...

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Detalles Bibliográficos
Autores principales: Seitz, Aaron P., Schumacher, Fabian, Baker, Jennifer, Soddemann, Matthias, Wilker, Barbara, Caldwell, Charles C., Gobble, Ryan M., Kamler, Markus, Becker, Katrin Anne, Beck, Sascha, Kleuser, Burkhard, Edwards, Michael J., Gulbins, Erich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647234/
https://www.ncbi.nlm.nih.gov/pubmed/31222488
http://dx.doi.org/10.1007/s00109-019-01800-1