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Cholesterol efflux alterations in adolescent obesity: role of adipose-derived extracellular vesical microRNAs

BACKGROUND: Macrophage cholesterol efflux capacity has been identified as a predictor for cardiovascular disease. We assessed the relationship between adipocyte-derived extracellular vesicle microRNAs and macrophage cholesterol efflux capacity. METHODS: We assessed an adolescent cohort (n = 93, Age,...

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Detalles Bibliográficos
Autores principales: Barberio, Matthew D., Kasselman, Lora J., Playford, Martin P., Epstein, Samuel B., Renna, Heather A., Goldberg, Madeleine, DeLeon, Joshua, Voloshyna, Iryna, Barlev, Ashley, Salama, Michael, Ferrante, Sarah C., Nadler, Evan P., Mehta, Nehal, Reiss, Allison B., Freishtat, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647309/
https://www.ncbi.nlm.nih.gov/pubmed/31331347
http://dx.doi.org/10.1186/s12967-019-1980-6