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Patient recruitment strategies for adaptive enrichment designs with time-to-event endpoints
BACKGROUND: Adaptive enrichment designs for clinical trials have great potential for the development of targeted therapies. They enable researchers to stop the recruitment process for a certain population in mid-course based on an interim analysis. However, adaptive enrichment designs increase the t...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647323/ https://www.ncbi.nlm.nih.gov/pubmed/31331277 http://dx.doi.org/10.1186/s12874-019-0800-2 |