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Carnitine Supplementation Attenuates Sunitinib-Induced Inhibition of AMP-Activated Protein Kinase Downstream Signals in Cardiac Tissues

This study has been initiated to investigate whether sunitinib (SUN) alters the expression of key genes engaged in mitochondrial transport and oxidation of long chain fatty acids (LCFA), and if so, whether these alterations should be viewed as a mechanism of SUN-induced cardiotoxicity, and to explor...

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Detalles Bibliográficos
Autores principales: Sayed-Ahmed, Mohamed M., Alrufaiq, Badr I., Alrikabi, Ammar, Abdullah, Mashan L., Hafez, Mohamed M., Al-Shabanah, Othman A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647422/
https://www.ncbi.nlm.nih.gov/pubmed/30644033
http://dx.doi.org/10.1007/s12012-018-9500-0