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Ex vivo modelling of the formation of inflammatory platelet-leucocyte aggregates and their adhesion on endothelial cells, an early event in sepsis

Septicaemia is an acute inflammatory reaction in the bloodstream to the presence of pathogen-associated molecular patterns. Whole blood stimulation assays capture endotoxin-induced formation of aggregates between platelets and leucocytes using flow cytometry. We wanted to assess extent of spontaneou...

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Detalles Bibliográficos
Autores principales: Alharbi, Azzah, Thompson, Jonathan P., Brindle, Nicholas P., Stover, Cordula M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647484/
https://www.ncbi.nlm.nih.gov/pubmed/30191349
http://dx.doi.org/10.1007/s10238-018-0526-1