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Imaging tumor acidosis: a survey of the available techniques for mapping in vivo tumor pH

Cancer cells are characterized by a metabolic shift in cellular energy production, orchestrated by the transcription factor HIF-1α, from mitochondrial oxidative phosphorylation to increased glycolysis, regardless of oxygen availability (Warburg effect). The constitutive upregulation of glycolysis le...

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Detalles Bibliográficos
Autores principales: Anemone, Annasofia, Consolino, Lorena, Arena, Francesca, Capozza, Martina, Longo, Dario Livio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647493/
https://www.ncbi.nlm.nih.gov/pubmed/30762162
http://dx.doi.org/10.1007/s10555-019-09782-9