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Imaging tumor acidosis: a survey of the available techniques for mapping in vivo tumor pH
Cancer cells are characterized by a metabolic shift in cellular energy production, orchestrated by the transcription factor HIF-1α, from mitochondrial oxidative phosphorylation to increased glycolysis, regardless of oxygen availability (Warburg effect). The constitutive upregulation of glycolysis le...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647493/ https://www.ncbi.nlm.nih.gov/pubmed/30762162 http://dx.doi.org/10.1007/s10555-019-09782-9 |