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Acetazolamide Mitigates Intracranial Pressure Spikes Without Affecting Functional Outcome After Experimental Hemorrhagic Stroke

Increased intracranial pressure (ICP) after stroke can lead to poor outcome and death. Novel treatments to combat ICP rises are needed. The carbonic anhydrase inhibitor acetazolamide diminishes cerebrospinal fluid (CSF) production, reduces ICP in healthy animals, and is beneficial for idiopathic int...

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Detalles Bibliográficos
Autores principales: Williamson, Michael R., Wilkinson, Cassandra M., Dietrich, Kristen, Colbourne, Frederick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647499/
https://www.ncbi.nlm.nih.gov/pubmed/30225552
http://dx.doi.org/10.1007/s12975-018-0663-6