Endolysosome and Autolysosome Dysfunction in Alzheimer’s Disease: Where Intracellular and Extracellular Meet

Disturbed proteostasis as reflected by a massive accumulation of misfolded protein aggregates is a central feature in Alzheimer’s disease. Proteostatic disturbances may be caused by a shift in protein production and clearance. Whereas rare genetic causes of the disease affect the production side, sp...

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Detalles Bibliográficos
Autores principales: van Weering, Jan R. T., Scheper, Wiep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Leading Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647502/
https://www.ncbi.nlm.nih.gov/pubmed/31165364
http://dx.doi.org/10.1007/s40263-019-00643-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647502/
https://www.ncbi.nlm.nih.gov/pubmed/31165364
http://dx.doi.org/10.1007/s40263-019-00643-1

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