The Alu neurodegeneration hypothesis: A primate-specific mechanism for neuronal transcription noise, mitochondrial dysfunction, and manifestation of neurodegenerative disease

It is hypothesized that retrotransposons have played a fundamental role in primate evolution and that enhanced neurologic retrotransposon activity in humans may underlie the origin of higher cognitive function. As a potential consequence of this enhanced activity, it is likely that neurons are susce...

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Detalles Bibliográficos
Autores principales: Larsen, Peter A., Lutz, Michael W., Hunnicutt, Kelsie E., Mihovilovic, Mirta, Saunders, Ann M., Yoder, Anne D., Roses, Allen D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647845/
https://www.ncbi.nlm.nih.gov/pubmed/28242298
http://dx.doi.org/10.1016/j.jalz.2017.01.017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647845/
https://www.ncbi.nlm.nih.gov/pubmed/28242298
http://dx.doi.org/10.1016/j.jalz.2017.01.017

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