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Studies on Osteocytes in Their 3D Native Matrix Versus 2D In Vitro Models

PURPOSE OF REVIEW: Osteocytes are responsible for mechanosensing and mechanotransduction in bone and play a crucial role in bone homeostasis. They are embedded in a calcified collagenous matrix and connected with each other through the lacuno-canalicular network. Due to this specific native environm...

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Detalles Bibliográficos
Autores principales: Zhang, Chen, Bakker, Astrid D., Klein-Nulend, Jenneke, Bravenboer, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647862/
https://www.ncbi.nlm.nih.gov/pubmed/31240566
http://dx.doi.org/10.1007/s11914-019-00521-1