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Comparison of PCR and Viable Count as a Method for Enumeration of Bacteria in an A/J Mouse Aerosol Model of Q Fever

Historically, disease progression in animal models of Q fever has been carried out using PCR to monitor the presence of Coxiella burnetii DNA in the host. However, the colonization and dissemination of other bacterial infections in animal models are tracked using viable counts, enabling an accurate...

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Detalles Bibliográficos
Autores principales: Hartley, M. Gill, Ralph, Esther, Norville, Isobel H., Prior, Joann L., Atkins, Timothy P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647910/
https://www.ncbi.nlm.nih.gov/pubmed/31379760
http://dx.doi.org/10.3389/fmicb.2019.01552