Quinazolinone Synthesis through Base-Promoted S(N)Ar Reaction of ortho-Fluorobenzamides with Amides Followed by Cyclization

[Image: see text] A transition-metal-free synthesis of quinazolin-4-ones by Cs(2)CO(3)-promoted S(N)Ar reaction of ortho-fluorobenzamides with amides followed by cyclization in dimethyl sulfoxide has been developed. The present procedure can provide efficient synthetic methods for the formation of b...

Descripción completa

Detalles Bibliográficos
Autores principales: Iqbal, Muhammad Asif, Lu, Le, Mehmood, Hina, Khan, Dost Muhammad, Hua, Ruimao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647956/
https://www.ncbi.nlm.nih.gov/pubmed/31459909
http://dx.doi.org/10.1021/acsomega.9b00699

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647956/
https://www.ncbi.nlm.nih.gov/pubmed/31459909
http://dx.doi.org/10.1021/acsomega.9b00699

Ejemplares similares