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C-Terminal Plays as the Possible Nucleation of the Self-Aggregation of the S-Shape Aβ(11–42) Tetramer in Solution: Intensive MD Study

[Image: see text] Amyloid beta (Aβ) peptides are characterized as the major factors associated with neuron death in Alzheimer’s disease, which is listed as the most common form of neurodegeneration. Disordered Aβ peptides are released from proteolysis of the amyloid precursor protein. The Aβ self-as...

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Detalles Bibliográficos
Autores principales: Tung, Nguyen Thanh, Derreumaux, Philippe, Vu, Van V., Nam, Pham Cam, Ngo, Son Tung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648102/
https://www.ncbi.nlm.nih.gov/pubmed/31460204
http://dx.doi.org/10.1021/acsomega.9b00992