Roles of Closed- and Open-Loop Conformations in Large-Scale Structural Transitions of l-Lactate Dehydrogenase

[Image: see text] The mechanism of l-lactate generation from pyruvate by l-lactate dehydrogenase (LDH) from the rabbit muscle was studied theoretically by the multistructural microiteration (MSM) method combined with the quantum mechanics/molecular mechanics (QM/MM)–ONIOM method, where the MSM metho...

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Detalles Bibliográficos
Autores principales: Suzuki, Kimichi, Maeda, Satoshi, Morokuma, Keiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648161/
https://www.ncbi.nlm.nih.gov/pubmed/31459393
http://dx.doi.org/10.1021/acsomega.8b02813

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648161/
https://www.ncbi.nlm.nih.gov/pubmed/31459393
http://dx.doi.org/10.1021/acsomega.8b02813

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