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Dissymmetry Factor Spectral Analysis Can Provide Useful Diastereomer Discrimination: Chiral Molecular Structure of an Analogue of (−)-Crispine A

[Image: see text] (1R,10bR)-1′-((R)-1,2-Dihydroxyethyl)-1-hydroxy-8,9-dimethoxy1,5,6,10b-tetrahydropyrrolo [2,1-a]isoquinolin-3(2H)-one, an analogue of (−)-crispine A, with three stereogenic centers is synthesized and its absolute configuration (AC) established using the combined information derived...

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Detalles Bibliográficos
Autores principales: Johnson, Jordan L., Nair, Divya Sadasivan, Pillai, Sarath Muraleedharan, Johnson, Didimos, Kallingathodi, Zabeera, Ibnusaud, Ibrahim, Polavarapu, Prasad L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648312/
https://www.ncbi.nlm.nih.gov/pubmed/31459760
http://dx.doi.org/10.1021/acsomega.8b03678