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Physicochemical Properties Govern the Activity of Potent Antiviral Flavones

[Image: see text] Ladanein (i.e., 5,6,7-trihydroxylated flavone) was demonstrated to act as a powerful virucidal agent toward a broad range of enveloped virus particles. Fe(III) coordination and pH are indeed among the key parameters that might favor both bioactivation of the flavone and consequent...

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Detalles Bibliográficos
Autores principales: Martin-Benlloch, Xavier, Haid, Sibylle, Novodomska, Alexandra, Rominger, Frank, Pietschmann, Thomas, Davioud-Charvet, Elisabeth, Elhabiri, Mourad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648324/
https://www.ncbi.nlm.nih.gov/pubmed/31459671
http://dx.doi.org/10.1021/acsomega.8b03332