Cargando…
Physicochemical Properties Govern the Activity of Potent Antiviral Flavones
[Image: see text] Ladanein (i.e., 5,6,7-trihydroxylated flavone) was demonstrated to act as a powerful virucidal agent toward a broad range of enveloped virus particles. Fe(III) coordination and pH are indeed among the key parameters that might favor both bioactivation of the flavone and consequent...
Autores principales: | Martin-Benlloch, Xavier, Haid, Sibylle, Novodomska, Alexandra, Rominger, Frank, Pietschmann, Thomas, Davioud-Charvet, Elisabeth, Elhabiri, Mourad |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2019
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648324/ https://www.ncbi.nlm.nih.gov/pubmed/31459671 http://dx.doi.org/10.1021/acsomega.8b03332 |
Ejemplares similares
-
Pharmacomodulation of the Antimalarial Plasmodione: Synthesis of Biaryl- and N-Arylalkylamine Analogues, Antimalarial Activities and Physicochemical Properties
por: Urgin, Karène, et al.
Publicado: (2017) -
Persicamidines—Unprecedented Sesquarterpenoids with Potent Antiviral Bioactivity against Coronaviruses
por: Keller, Lena, et al.
Publicado: (2023) -
A Class of Valuable (Pro-)Activity-Based Protein Profiling
Probes: Application to the Redox-Active Antiplasmodial Agent, Plasmodione
por: Cichocki, Bogdan Adam, et al.
Publicado: (2021) -
Antimalarial NADPH-Consuming Redox-Cyclers As Superior Glucose-6-Phosphate Dehydrogenase Deficiency Copycats
por: Bielitza, Max, et al.
Publicado: (2015) -
Hairy Roots of Scutellaria spp. (Lamiaceae) as Promising Producers of Antiviral Flavones
por: Stepanova, Anna Yurievna, et al.
Publicado: (2021)