Accurate prediction of boundaries of high resolution topologically associated domains (TADs) in fruit flies using deep learning

Genomes are organized into self-interacting chromatin regions called topologically associated domains (TADs). A significant number of TAD boundaries are shared across multiple cell types and conserved across species. Disruption of TAD boundaries may affect the expression of nearby genes and could le...

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Detalles Bibliográficos
Autores principales: Henderson, John, Ly, Vi, Olichwier, Shawn, Chainani, Pranik, Liu, Yu, Soibam, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648328/
https://www.ncbi.nlm.nih.gov/pubmed/31049567
http://dx.doi.org/10.1093/nar/gkz315

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648328/
https://www.ncbi.nlm.nih.gov/pubmed/31049567
http://dx.doi.org/10.1093/nar/gkz315

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