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Accurate prediction of boundaries of high resolution topologically associated domains (TADs) in fruit flies using deep learning
Genomes are organized into self-interacting chromatin regions called topologically associated domains (TADs). A significant number of TAD boundaries are shared across multiple cell types and conserved across species. Disruption of TAD boundaries may affect the expression of nearby genes and could le...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648328/ https://www.ncbi.nlm.nih.gov/pubmed/31049567 http://dx.doi.org/10.1093/nar/gkz315 |