The structure of human EXD2 reveals a chimeric 3′ to 5′ exonuclease domain that discriminates substrates via metal coordination

EXD2 (3′-5′ exonuclease domain-containing protein 2) is an essential protein with a conserved DEDDy superfamily 3′-5′ exonuclease domain. Recent research suggests that EXD2 has two potential functions: as a component of the DNA double-strand break repair machinery and as a ribonuclease for the regul...

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Detalles Bibliográficos
Autores principales: Park, Jumi, Lee, Song-Yi, Jeong, Hanbin, Kang, Myeong-Gyun, Van Haute, Lindsey, Minczuk, Michal, Seo, Jeong Kon, Jun, Youngsoo, Myung, Kyungjae, Rhee, Hyun-Woo, Lee, Changwook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648332/
https://www.ncbi.nlm.nih.gov/pubmed/31127291
http://dx.doi.org/10.1093/nar/gkz454

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648332/
https://www.ncbi.nlm.nih.gov/pubmed/31127291
http://dx.doi.org/10.1093/nar/gkz454

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